Efficient Segmentation of Brain Tumor Using FL-SNM with a Metaheuristic Approach to Optimization

J Med Syst. 2019 Jan 2;43(2):25. doi: 10.1007/s10916-018-1135-y.

Abstract

Nowadays, automatic tumor detection from brain images is extremely significant for many diagnostic as well as therapeutic purposes, due to the unpredictable shape and appearance of tumors. In medical image analysis, the automatic segmentation of tumors from brain using magnetic resonance imaging (MRI) data is the most critical issue. Existing research has some limitations, such as high processing time and lower accuracy, because of the time required for the training process. In this research, a new automatic segmentation process is introduced using machine learning and a swarm intelligence scheme. Here, a fuzzy logic with spiking neuron model (FL-SNM) is proposed for segmenting the brain tumor region in MR images. Initially, input images are preprocessed to remove Gaussian and Poisson noise using a modified Kuan filter (MKF). In the MKF, the optimal selection of the minimum MSE of image pixels is achieved using a random search algorithm (RSA), which improves the peak signal-to-noise ratio (PSNR). Then, the image is smoothed using an anisotropic diffusion filter (ADF) to reduce the over-filtering problem. Afterwards, to extract statistical texture features, Fisher's linear-discriminant analysis (FLDA) is used. Finally, extracted features are transferred to the FL-SNM process and this scheme effectively segments the tumor region. In FL-SNM, the consequent parameters such as weight and bias play an important role in segmenting the region. Therefore, optimizing the weight parameter values using a chicken behavior-based swarm intelligence (CSI) algorithm, is proposed. The proposed (FL-SNM) scheme attained better performance in terms of high accuracy (94.87%), sensitivity (92.07%), specificity (99.34%), precision rate (89.36%), recall rate (88.39%), F-measure (95.06%), G-mean (95.63%), and DSC rate (91.2%), compared to existing convolutional neural networks (CNNs) and hierarchical self-organizing maps (HSOMs).

Keywords: Diffusion filter; Discriminant analysis; Fuzzy logic; Kuan filter; Linear process; Optimization; Spiking neuron model; Swarm intelligence.

MeSH terms

  • Algorithms
  • Brain Neoplasms / diagnostic imaging*
  • Brain Neoplasms / pathology*
  • Fuzzy Logic*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Machine Learning*
  • Magnetic Resonance Imaging / methods
  • Neural Networks, Computer
  • Signal-To-Noise Ratio