Serious Neurological Complication Resulting from Inadvertent Intradiscal Injection During Fluoroscopically Guided Interlaminar Epidural Steroid Injection

Cardiovasc Intervent Radiol. 2019 May;42(5):775-778. doi: 10.1007/s00270-018-2151-5. Epub 2019 Jan 2.

Abstract

We describe the case of a 30-year-old patient who was referred for lumbar epidural corticosteroid injection due to right L5 radiculopathy. Two months earlier, MRI demonstrated a right large paracentral L4-L5 disk extrusion causing disabling L5 radiculopathy. The L4-L5 level was selected for interlaminar injection, using fluoroscopic guidance. During injection, the patient developed severe pain in both lower extremities. Thus, the procedure was immediately terminated. Paraplegia occurred within several minutes. Urgent lumbar spine CT and MRI demonstrated contrast material in a massive extruded disk fragment and substantial increase in size of the disk extrusion compared to pre-injection MRI. Emergency surgery was performed for lumbar decompression and discectomy. Although rare, serious neurological complication can result from inadvertent intradiscal injection of contrast material during lumbar epidural injection. This case illustrates the importance of recognizing the possibility of dynamic change in the size of an extruded disk fragment when the MRI precedes injection by a substantial time interval. LEVEL OF EVIDENCE: IV, Case Series.

Keywords: Intervertebral disk displacement; Spinal cord compression; Spinal injection steroids; Spinal nerve roots.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Cortex Hormones / administration & dosage
  • Adult
  • Contrast Media / administration & dosage
  • Contrast Media / adverse effects*
  • Diskectomy
  • Extravasation of Diagnostic and Therapeutic Materials / complications*
  • Fluoroscopy / methods
  • Humans
  • Injections
  • Injections, Epidural / adverse effects
  • Injections, Epidural / methods
  • Intervertebral Disc Displacement / complications*
  • Intervertebral Disc Displacement / diagnostic imaging
  • Lumbar Vertebrae / diagnostic imaging
  • Lumbosacral Region / diagnostic imaging
  • Magnetic Resonance Imaging
  • Paraplegia / chemically induced*
  • Radiculopathy / drug therapy*
  • Radiculopathy / etiology
  • Radiography, Interventional / methods*
  • Tomography, X-Ray Computed

Substances

  • Adrenal Cortex Hormones
  • Contrast Media