Vaginosis. Vaginal microbiota

Enferm Infecc Microbiol Clin (Engl Ed). 2019 Nov;37(9):592-601. doi: 10.1016/j.eimc.2018.11.009. Epub 2018 Dec 26.
[Article in English, Spanish]

Abstract

The latest advances in the vaginal microbiome and molecular diagnosis of bacterial vaginosis have allowed for a better knowledge of this entity, characterising aspects of its pathogenesis and the establishment of the vaginal biolayer, the models and new theories of its aetiology, how it is transmitted, with it being considered nowadays as a probable sexually transmitted infection, the separation of other entities such as aerobic vaginosis, its molecular diagnosis and treatment with new molecules to prevent frequent relapses. This entity and the study of the vaginal microbiome have made it possible to consider these infections as a polymicrobial syndrome, putting an end to the dogma: one microorganism, one disease. In addition, a lesser-known entity such as aerobic vaginosis and the methods for its detection are updated.

Keywords: Aerobic vaginitis; Bacterial vaginosis; Microbiota vaginal; Vaginal microbiota; Vaginitis aerobia; Vaginosis bacteriana.

Publication types

  • Review

MeSH terms

  • Anti-Bacterial Agents / adverse effects
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Bacteriological Techniques
  • Coinfection / epidemiology
  • Coinfection / microbiology
  • Female
  • Humans
  • Lactobacillus / physiology
  • Microbiota* / drug effects
  • Mycoses / diagnosis
  • Mycoses / drug therapy
  • Mycoses / epidemiology
  • Mycoses / microbiology
  • Pregnancy
  • Pregnancy Complications, Infectious / microbiology
  • Prevalence
  • Sexually Transmitted Diseases, Bacterial / epidemiology
  • Sexually Transmitted Diseases, Bacterial / microbiology
  • Spermatocidal Agents / adverse effects
  • Vagina / microbiology*
  • Vaginal Smears
  • Vaginosis, Bacterial / diagnosis
  • Vaginosis, Bacterial / drug therapy
  • Vaginosis, Bacterial / epidemiology
  • Vaginosis, Bacterial / microbiology*

Substances

  • Anti-Bacterial Agents
  • Spermatocidal Agents