Rheumatoid arthritis revisited

Med Hypotheses. 2019 Jan:122:56. doi: 10.1016/j.mehy.2018.10.007. Epub 2018 Oct 11.

Abstract

The generally accepted theory of the etiopathology of rheumatoid arthritis has not led to a breakthrough so far, and the root cause of RA is still unknown. Surgical experience does not support the idea that the damage in the joint is caused by synovitis. Synovial tissue does not spread on the surface of the cartilage and thus destroy it, and neither is the erosion caused by the synovial tissue. Macroscopically and microscopically synovitis in RA is no different to synovitis in arthrosis. Perhaps the etiopathogenesis should once more be reconsidered.

Publication types

  • Letter

MeSH terms

  • Arthritis, Rheumatoid / etiology
  • Arthritis, Rheumatoid / physiopathology*
  • Autoimmune Diseases
  • Cartilage / physiopathology
  • Humans
  • Immune System
  • Inflammation
  • Osteoarthritis / physiopathology
  • Synovial Membrane / physiopathology*
  • Temporal Arteries / pathology