Objective: To investigate the correlation among the serum low density lipoprotein subfractions, lipoprotein a and other routine indices.
Methods: Medical students who didn 't experience cardiovascular events were recruited at a university in Nanjing City, their physical indicators were measured( including height, weight, waist circumference and hip circumference) and fasting blood was collected to detect the seven items of serum lipid. Lipoprint system was used to detect low density lipoprotein subfractions, the correlation among the indices was analyzed ultimately.
Results: A total of 84 students( 40 male and 44 female) at the age of 20-29 were enrolled in the study. Levels of body mass index, waist-to-hip ratio, very low density lipoprotein, small dense low density lipoprotein in male were significantly higher than those in female, while levels ofhigh density lipoprotein, apolipoprotein A1, intermediate density lipoprotein and mean low density lipoprotein size in male were significantly lower than those in female( P < 0. 05). In this population, the abnormal rate of lipoprotein a reached 27. 4% and was only significantly positively correlated with high density lipoprotein( r = 0. 265, P = 0. 015), and the mean low density lipoprotein size was significantly negatively correlated with waist-to-hip ratio, triglyceride and small dense low density lipoprotein etc. ( P < 0. 05).
Conclusion: Male medical students have more risk factors of angiocardiopathy than young women, and the abnormal rate of serum lipoprotein a in medical students is higher.
Keywords: high density lipoprotein; lipoprotein a; low density lipoprotein subfractions; mean low density lipoprotein size.