Revisiting Successful Aging With HIV Through a Revised Biopsychosocial Model: An Update of the Literature

J Assoc Nurses AIDS Care. 2019 Jan-Feb;30(1):5-14. doi: 10.1097/JNC.0000000000000029.

Abstract

The concept of successful aging was recognized only recently by HIV researchers because people living with HIV (PLWH) in the early epidemic were not expected to survive. With the introduction of antiretrovirals that block viral replication, PLWH are now aging with HIV. Given the complex nature of HIV within the social, economic, and political climates in which it occurs, a holistic model of successful aging is needed to guide researchers and clinicians. Several overarching models exist, but must be updated for rapidly advancing HIV and aging research agendas. We provide an updated, adapted, and integrated biopsychosocial model of successful aging with HIV based on the principles of Baltes and Baltes (1998) on 8 essential components of successful aging: (a) length of life, (b) biological health, (c) mental health, (d) cognitive efficiency, (e) social competence, (f) productivity, (g) personal control, and (h) life satisfaction. Clinical practice and research implications are highlighted.

Trial registration: ClinicalTrials.gov NCT03122288 NCT02758093.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Aged, 80 and over
  • Aging / physiology
  • Aging / psychology*
  • Anti-HIV Agents / adverse effects
  • Anti-HIV Agents / therapeutic use*
  • Antiretroviral Therapy, Highly Active* / adverse effects
  • Cognition Disorders / drug therapy
  • Cognition Disorders / epidemiology
  • Cognition Disorders / psychology
  • Female
  • HIV Infections / drug therapy
  • HIV Infections / physiopathology
  • HIV Infections / psychology*
  • HIV Long-Term Survivors / psychology*
  • Humans
  • Longevity / drug effects
  • Mental Health*
  • Personal Satisfaction*
  • Quality of Life / psychology*
  • Social Adjustment

Substances

  • Anti-HIV Agents

Associated data

  • ClinicalTrials.gov/NCT03122288
  • ClinicalTrials.gov/NCT02758093