Objective: evaluate the retinal morphometric parameters of the reconvalescents in remote period after acute radi-ation sickness.
Materials and methods: A complete ophthalmologic examination was carried out on 7 reconvalescents of acuteradiation sickness. The examined are divided into two subgroups: 1) patients with macular degeneration of the reti-na (8 eyes); 2) patients without clinical signs of macular pathology (6 eyes). Parameters of the retina in the cen-tral retina zone studied using the method of optical coherence tomography. To evaluate the results of surveys usedstatistical methods: average values of quantitative indicators calculation, estimation of probability difference byStudent's method.
Results: Optical coherence tomography revealed a statistically significant increase of the thickness of the retina inthe fovea in all reconvalescents of acute radiation sickness.
Conclusions: It was shown that the thickness of the retina in the fovea and paramacular zone in persons who suf-fered acute radiation sickness is significantly higher than in the control. These changes observed in all reconvalis-cents ARS - both in person with sings of macular degeneration, and in those whose clinical manifestations were notdetected. The presence of a correlation between the volume of the retina in the macular zone and the documentedradiation dose of the study group emphasizes the perspectives of next OCT examination of the retina of reconvales-cents of ARS to study the mechanism of retina's damage in this category of victims of the Chornobyl accident.
Meta: otsinyty morfometrychni parametry sitkivky u rekonvalestsentiv u viddalenomu periodi pislia perenesenoïgostroï promenevoï khvoroby.Materialy i metody. Provedeno povne oftal'mologichne obstezhennia 7 rekonvalestsentiv gostroï promenevoïkhvoroby (GPKh). Obstezheni rozpodileni na dvi pidgrupy: 1) patsiienty zi vstanovlenym diagnozom makuliarnoï dege-neratsiï sitkivky (8 ocheĭ); 2) patsiienty, iaki ne maly klinichnykh oznak patologiï makuly (6 ocheĭ). Parametry sitkivkyv tsentral'niĭ zoni vyvchaly za dopomogoiu metodu optychnoï kogerentnoï tomografiï. Dlia otsinky rezul'tativ obs-tezhen' vykorystani statystychni metody: obchyslennia serednikh znachen' kil'kisnykh pokaznykiv, otsinkavirogidnosti riznytsi za metodom St’iudenta.Rezul'taty. Optychna kogerentna tomografiia zasvidchyla statystychno dostovirne zbil'shennia tovshchyny sitchastoïobolonky u foveoli vsikh rekonvalestsentiv GPKh.Vysnovky. Pokazano, shcho tovshchyna sitchastoï obolonky u foveoli i paramakuliarniĭ zoni v osib, iaki perenesly GPKh,virogidno bil'sha, nizh u kontroli. Tsi zminy sposterigaiut'sia u vsikh rekonvalestsentiv GPKh – iak u osib z proiavamymakuliarnoï dystrofiï, tak i u tykh, v kogo ïï klinichnykh proiaviv ne bulo vyiavleno. Naiavnist' koreliatsiĭnogo zv'iaz-ku mizh ob’iemom sitkivky u makuliarniĭ zoni i dokumentovanoiu dozoiu oprominennia doslidzhuvanoï grupy pidkres-liuie perspektyvnist' podal'shykh doslidzhen' sitchastoï obolonky rekonvalestsentiv GPKh za dopomogoiu optychnoïkogerentnoï tomografiï dlia vyvchennia mekhanizmu ushkodzhennia sitkivky u tsiieï kategoriï postrazhdalykh vnaslidokChornobyl's'koï katastrofy.
Keywords: Optical coherence tomography; acute radiation sickness; macular degeneration; macular zone of the retina; reconvalescents.
P. Fedirko, T. Babenko, R. Dorichevska, N. Garkava, L. Grek, V. Vasylenko, S. Masiuk.