Ultrasonic synthesis of Oct. trans-Br2Cu(N ∩ N)2 Jahn-Teller distortion complex: XRD-properties, solvatochromism, thermal, kinetic and DNA-binding evaluations

Ismail Warad; Sharif Musameh; Ashraf Sawafta; Paula Brandão; Carlos José Tavares; Abdelkader Zarrouk; Sameer Amereih; Anas Al Ali; Rami Shariah

doi:10.1016/j.ultsonch.2018.12.019

Ultrasonic synthesis of Oct. trans-Br₂Cu(N ∩ N)₂ Jahn-Teller distortion complex: XRD-properties, solvatochromism, thermal, kinetic and DNA-binding evaluations

Ultrason Sonochem. 2019 Apr:52:428-436. doi: 10.1016/j.ultsonch.2018.12.019. Epub 2018 Dec 12.

Authors

Ismail Warad¹, Sharif Musameh², Ashraf Sawafta³, Paula Brandão⁴, Carlos José Tavares⁵, Abdelkader Zarrouk⁶, Sameer Amereih⁷, Anas Al Ali⁸, Rami Shariah⁹

Affiliations

¹ Department of Chemistry, AN-Najah National University, P.O. Box 7, Nablus, Palestine. Electronic address: warad@najah.edu.
² Department of Physics, AN-Najah National University, P.O. Box 7, Nablus, Palestine.
³ Biology and Biotechnology Department, An-Najah National University, P.O. Box 7, Nablus, Palestine.
⁴ Department of Chemistry, CICECO-Aveiro Institute of Materials, University of Aveiro, 3810-193 Aveiro, Portugal.
⁵ Center of Physics, University of Minho, Campus of Azurem, 4804-533 Guimaraes, Portugal.
⁶ Laboratory of Materials, Nanotechnology and Environment, Mohammed V University, Faculty of Science, 4Av. Ibn Battuta, B.P. 1014 Rabat, Morocco.
⁷ Department of Chemistry, Science College, Palestine Technical University, P.O. Box 7, Tulkarm, Palestine.
⁸ Department of Chemistry, AN-Najah National University, P.O. Box 7, Nablus, Palestine.
⁹ Basic Science Department, Applied Science Private University, Al-Arab St. 21, Amman, Jordan.

PMID: 30573435
DOI: 10.1016/j.ultsonch.2018.12.019

Abstract

Under mode of ultrasonic vibration, the neutral octahedral mononuclear [trans-CuBr₂(N ∩ N)₂]·3H₂O complex with N ∩ N = 2,2-dimethylpropane-1,3-diamine was obtained. The structure of the desired complex was characterized by UV-Vis. spectroscopy, FT-IR, EDX, MS, SEM, TG/DTA and CHN-analysis. The octahedral-structure of the desired Cu(II) complex was proven via XRD single-crystal diffraction and its molecular interactions were computed by Hirschfeld surface analysis. Alcohol (as solvent) and short ultrasonic vibration dose period played a critical role in sonochemistry synthesis of octahedral neutral trans-CuBr₂(N ∩ N)₂ complex instead of trigonal bi-pyramidal monocation [CuBr(N ∩ N)₂]Br one. Due to the Jahn-Teller effect, the complex exhibited a trans bonds elongation along Br-Cu-Br axis originating a distorted-octahedral Cu(II), as revealed by the XRD measurements (Br-Cu = 3.04 Å). Therefore, the Solvatochromic behavior of the complex was successfully performed since the trans di-bromide ions are loosely coordinated to Cu(II) center, the change in complex solutions colors by using different solvents which can be detected even by naked-eye supported atypical Jahn-Teller elongation effect formation. TG/DTA and Flynn Wall Ozawa (FWO) isoconversional kinetic methods were applied for the complex to figure out the thermal behavior, kinetic of the ligands de-structured and estimate its Ea/α relation. The complex binding mode to the CT-DNA was examined by UV-vis. spectroscopic, melting curve, CV and viscosity tests. The complex exhibited very strong DNA binding via an intercalation mode of coordination with K_b = 6.5 × 10⁵ value.

Keywords: Cu(II); DNA; FWO isoconversional; Jahn-Teller; Solvatochromism; TGA; XRD.

Publication types

Review

MeSH terms

Animals
Cattle
Chemistry Techniques, Synthetic
Coordination Complexes / chemistry*
Coordination Complexes / metabolism*
Copper / chemistry*
Crystallography, X-Ray
DNA / metabolism*
Diamines / chemistry
Electrochemistry
Kinetics
Ligands
Models, Molecular
Molecular Conformation
Solvents / chemistry*
Stereoisomerism
Ultrasonic Waves*

Substances

Coordination Complexes
Diamines
Ligands
Solvents
Copper
DNA