Hamartomas of skin and soft tissue

Semin Diagn Pathol. 2019 Jan;36(1):48-61. doi: 10.1053/j.semdp.2018.12.001. Epub 2018 Dec 11.

Abstract

Hamartomas are benign lesions composed of aberrant disorganized growth of mature tissues. Choristomas are similar, except that they are composed of tissues not normally found at the anatomic site in which the lesion is arising. A wide range of hamartomas and choristomas can arise in the skin and soft tissue. Some of these may cause diagnostic difficulty and potentially be mistaken for neoplasms. Some neoplasms may resemble hamaratomas. Here we review the current clinical and pathologic features of these lesions, both common and rare, and discuss how to distinguish them from other entities in the differential diagnosis.

Keywords: Choristoma; Ectopic; Hamartoma; Heterotopia; Nevus sebaceus; Vascular malformation.

Publication types

  • Review

MeSH terms

  • Choristoma / pathology*
  • Diagnosis, Differential
  • Hamartoma / pathology*
  • Humans
  • Skin Neoplasms / pathology*
  • Soft Tissue Neoplasms / pathology*