Gadolinium to the rescue for mechanical thrombectomy in acute ischemic stroke

Interv Neuroradiol. 2019 Jun;25(3):301-304. doi: 10.1177/1591019918815298. Epub 2018 Dec 19.

Abstract

Introduction: Mechanical thrombectomy in the setting of acute ischemic stroke (AIS) requires cerebral digital subtraction angiography (DSA), typically performed with iodinated contrast medium. We present a case of emergent cerebral DSA and mechanical thrombectomy using gadolinium-based contrast for cerebral DSA in a patient with a history of anaphylaxis to iodinated contrast agents (ICs).

Case report: A 72-year-old man developed left ventricle assist device thrombus while on anticoagulation. During hospitalization he suffered right middle cerebral artery occlusion with a National Institutes of Health stroke scale score of 10. He had a history of anaphylaxis and the advanced directives revealed do not resuscitate/do not intubate status. We performed an emergent DSA as part of thrombectomy procedure using gadolinium-based contrast mixed in 1:1 proportion with normal saline. The images obtained were of adequate quality and the patient underwent successful thrombectomy with modified thrombolysis in cerebral infarction 2B recanalization.

Conclusion: Gadolinium-based contrast agents could be effective alternatives for cerebral DSA in patients undergoing mechanical thrombectomy for AIS who have a history of anaphylactic reaction to ICs.

Keywords: Gadolinium; allergy; angiogram; contrast; stroke; thrombectomy.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anaphylaxis / prevention & control
  • Angiography, Digital Subtraction / methods*
  • Brain Ischemia / diagnostic imaging*
  • Brain Ischemia / surgery*
  • Cerebral Infarction / diagnostic imaging
  • Cerebral Infarction / surgery
  • Contrast Media*
  • Drug Hypersensitivity
  • Gadolinium*
  • Heart-Assist Devices
  • Humans
  • Male
  • Stroke / diagnostic imaging*
  • Stroke / surgery*
  • Thrombectomy / methods*

Substances

  • Contrast Media
  • Gadolinium