Molecular Mechanisms and Pathophysiology of Ischemia-Reperfusion Injury

Int J Mol Sci. 2018 Dec 18;19(12):4093. doi: 10.3390/ijms19124093.

Authors

Arnau Panisello-Roselló¹, Joan Roselló-Catafau²

Affiliations

¹ Ischemia-Reperfusion Unit, Experimental Pathology Department, Institut d'Insvestigacions Biomèdiques de Barcelona (IIBB), Spanish Research Council, 08036 Barcelona, Catalonia, Spain. arnau.panisello.rosello@gmail.com.
² Ischemia-Reperfusion Unit, Experimental Pathology Department, Institut d'Insvestigacions Biomèdiques de Barcelona (IIBB), Spanish Research Council, 08036 Barcelona, Catalonia, Spain. jrcbam@iibb.csic.es.

Abstract

Ischemia-reperfusion injury (IRI) is a major cause of graft loss and dysfunction in clinical transplantation and organ resection. [...].

Publication types

Editorial

MeSH terms

Apoptosis / genetics
Graft Rejection / genetics*
Graft Rejection / physiopathology
Humans
Liver Transplantation / adverse effects
Nitric Oxide / genetics
Proto-Oncogene Proteins c-akt / genetics
Reperfusion Injury / genetics*
Reperfusion Injury / physiopathology
Signal Transduction
TOR Serine-Threonine Kinases / genetics

Substances

Nitric Oxide
Proto-Oncogene Proteins c-akt
TOR Serine-Threonine Kinases