[Expert centre Cancer du sein et Grossesse (CALG): Concordance between the proposed therapeutics and those finally received]

Abstract

Objective: Breast cancer associated with pregnancy (CSAG) is a rare condition whose management justifies the use of expert center. The Pregnancy-Associated Cancer Network (CALG) was created in France to optimize therapeutic management. The objective of our study was to evaluate its impact on the therapeutic management of CSAGs and the discrepancy rate between the CALG proposal and the treatment performed.

Method: A retrospective study including 58 CSAGs for which the opinion of the CALG network was solicited between January 2015 and November 2017. A questionnaire was addressed to the practitioner requesting the network. These practitioners were contacted to know the treatments received by the patient to assess the discrepancy rate.

Results: In 70% of the cases, the CALG network was solicited before any therapeutic treatment. When the opinion was requested after initiation of therapy, the discrepancy rate between the CALG proposal and the one practiced was 47%. Of the 46 physicians contacted, the response rate was 62.5% (30/46). In 90% of cases, the therapy proposed by the CALG network was the one received by the patient.

Conclusion: This study emphasizes the need to refer to an expert center before treatment of a CSAG and the need for the contribution of doctors requesting the expert center to inform them of the follow-up of patients and children.

Keywords: Breast cancer associated with pregnancy; Cancer associé à la Grossesse (CALG) network; Cancer du sein associé à la grossesse; Centre expert; Multidisciplinary team (MDT) meetings; Réseau cancer associé à La grossesse (CALG); Réunion de concertation pluridisciplinaire.