Avian Influenza A(H9N2) Virus in Poultry Worker, Pakistan, 2015

Emerg Infect Dis. 2019 Jan;25(1):136-139. doi: 10.3201/eid2501.180618.

Abstract

Avian influenza A(H9N2) virus isolated from a poultry worker in Pakistan in 2015 was closely related to viruses detected in poultry farms. Observed mutations in the hemagglutinin related to receptor-binding affinity and antigenicity could affect cross-reactivity with prepandemic H9N2 vaccine strains.

Keywords: Pakistan; Surveillance; avian influenza; evolution; influenza; influenza A(H9N2); poultry workers; viruses; zoonoses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Cross Reactions
  • Epidemiological Monitoring
  • Epitopes
  • Farmers
  • Hemagglutinin Glycoproteins, Influenza Virus / genetics*
  • Humans
  • Influenza A Virus, H9N2 Subtype / genetics*
  • Influenza A Virus, H9N2 Subtype / immunology
  • Influenza A Virus, H9N2 Subtype / isolation & purification
  • Influenza Vaccines / immunology*
  • Influenza, Human / epidemiology
  • Influenza, Human / virology*
  • Male
  • Mutation
  • Pakistan / epidemiology
  • Poultry
  • Zoonoses

Substances

  • Epitopes
  • Hemagglutinin Glycoproteins, Influenza Virus
  • Influenza Vaccines