Isolation and Full-Genome Characterization of Nipah Viruses from Bats, Bangladesh

Emerg Infect Dis. 2019 Jan;25(1):166-170. doi: 10.3201/eid2501.180267.

Abstract

Despite molecular and serologic evidence of Nipah virus in bats from various locations, attempts to isolate live virus have been largely unsuccessful. We report isolation and full-genome characterization of 10 Nipah virus isolates from Pteropus medius bats sampled in Bangladesh during 2013 and 2014.

Keywords: Bangladesh; Nipah virus; Pteropus medius; bats; enrichment; full-genome characterization; henipavirus; isolation; next-generation sequencing; viruses; zoonoses.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Bangladesh
  • Chiroptera / virology*
  • Disease Reservoirs / virology*
  • Genome, Viral / genetics*
  • Geography
  • Henipavirus Infections / veterinary*
  • Henipavirus Infections / virology
  • Humans
  • Nipah Virus / genetics*
  • Nipah Virus / isolation & purification
  • Phylogeny
  • Zoonoses