Electrochemical Enantiomer Recognition Based on sp³-to-sp² Converted Regenerative Graphene/Diamond Electrode

Jingyao Gao; Haoyang Zhang; Chen Ye; Qilong Yuan; Kuan W A Chee; Weitao Su; Aimin Yu; Jinhong Yu; Cheng-Te Lin; Dan Dai; Li Fu

doi:10.3390/nano8121050

Electrochemical Enantiomer Recognition Based on sp³-to-sp² Converted Regenerative Graphene/Diamond Electrode

Nanomaterials (Basel). 2018 Dec 14;8(12):1050. doi: 10.3390/nano8121050.

Authors

Jingyao Gao¹, Haoyang Zhang², Chen Ye³, Qilong Yuan^{4

5}, Kuan W A Chee^{6

7}, Weitao Su⁸, Aimin Yu⁹, Jinhong Yu¹⁰, Cheng-Te Lin¹¹, Dan Dai¹², Li Fu¹³

Affiliations

¹ Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. gaojingyao@nimte.ac.cn.
² College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China. zhanghaoyang@hdu.edu.cn.
³ Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. yechen@nimte.ac.cn.
⁴ Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. Qilong.Yuan@nottingham.edu.cn.
⁵ Department of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham, Ningbo 315100, China. Qilong.Yuan@nottingham.edu.cn.
⁶ Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. Kuan.Chee@nottingham.edu.cn.
⁷ Department of Electrical and Electronic Engineering, Faculty of Science and Engineering, University of Nottingham, Ningbo 315100, China. Kuan.Chee@nottingham.edu.cn.
⁸ College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China. suweitao@hdu.edu.cn.
⁹ Department of Chemistry and Biotechnology, Faculty of Science, Engineering and Technology, Swinburne University of Technology, Hawthorn, VIC 3122, Australia. aiminyu@swin.edu.au.
¹⁰ Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. yujinhong@nimte.ac.cn.
¹¹ Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. linzhengde@nimte.ac.cn.
¹² Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering (NIMTE), Chinese Academy of Sciences, Ningbo 315201, China. daidan@nimte.ac.cn.
¹³ College of Materials and Environmental Engineering, Hangzhou Dianzi University, Hangzhou 310018, China. fuli@hdu.edu.cn.

Abstract

It is of great significance to distinguish enantiomers due to their different, even completely opposite biological, physiological and pharmacological activities compared to those with different stereochemistry. A sp³-to-sp² converted highly stable and regenerative graphene/diamond electrode (G/D) was proposed as an enantiomer recognition platform after a simple β-cyclodextrin (β-CD) drop casting process. The proposed enantiomer recognition sensor has been successfully used for d and l-phenylalanine recognition. In addition, the G/D electrode can be simply regenerated by half-minute sonication due to the strong interfacial bonding between graphene and diamond. Therefore, the proposed G/D electrode showed significant potential as a reusable sensing platform for enantiomer recognition.

Keywords: chemical vapor deposition; electronic materials; enantiomer recognition; graphene; phenylalanine.