Disseminated Bartonella henselae disease mimicking Langerhans' cell histiocytosis

Athanasia Apsemidou; Kerstin Rauwolf; Athanasios Tragiannidis; Angela Brentrup; Manfred Schiborr; Karsten Becker; Martina Ahlmann; Andreas H Groll

doi:10.1002/pbc.27573

Disseminated Bartonella henselae disease mimicking Langerhans' cell histiocytosis

Pediatr Blood Cancer. 2019 Apr;66(4):e27573. doi: 10.1002/pbc.27573. Epub 2018 Dec 17.

Authors

Athanasia Apsemidou^{1

2}, Kerstin Rauwolf¹, Athanasios Tragiannidis^{1

2}, Angela Brentrup³, Manfred Schiborr⁴, Karsten Becker⁵, Martina Ahlmann¹, Andreas H Groll¹

Affiliations

¹ Infectious Disease Research Program, Center for Bone Marrow Transplantation, Department of Pediatric Hematology and Oncology, Children's University Hospital Münster, Münster, Germany.
² 2nd Pediatric Department, Aristotle University of Thessaloniki, AHEPA Hospital, Thessaloniki, Greece.
³ Department of Neurosurgery, University Hospital Münster, Münster, Germany.
⁴ Institute of Clinical Radiology, University Hospital Münster, Münster, Germany.
⁵ Institute of Medical Microbiology, University Hospital Münster, Münster, Germany.

PMID: 30556266
DOI: 10.1002/pbc.27573

Abstract

Bartonella henselae, the causative agent of cat-scratch disease, has been recognized to be responsible for a broad range of clinical syndromes. We report the case of a patient with disseminated B. henselae infection mimicking Langerhans cell histiocytosis at presentation and its successful management with neurosurgery, prolonged antibacterial therapy, and observation.

Keywords: bartonellosis; children; diagnosis; histiocytosis; management; osteonecrosis.

Publication types

Case Reports

MeSH terms

Bartonella henselae*
Cat-Scratch Disease* / diagnosis
Cat-Scratch Disease* / therapy
Child
Diagnosis, Differential
Female
Histiocytosis, Langerhans-Cell* / diagnosis
Histiocytosis, Langerhans-Cell* / therapy
Humans