Highly Pathogenic Avian H7N9 Influenza Viruses: Recent Challenges

Trends Microbiol. 2019 Feb;27(2):93-95. doi: 10.1016/j.tim.2018.11.008. Epub 2018 Dec 12.

Abstract

Novel highly pathogenic avian influenza (HPAI) H7N9 viruses of the fifth epidemic wave infect humans and poultry. Recently, HPAI H7N9 viruses have evolved into different subtypes and genotypes, exhibited heightened virulence in mammals, and extended their host range, thereby posing a potential threat to public health and the poultry industry.

Keywords: H7N9 virus; evolution; influenza A virus; pathogenicity; transmissibility.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Epidemics
  • Evolution, Molecular
  • Genotype
  • Host Specificity
  • Humans
  • Influenza A Virus, H7N9 Subtype / genetics*
  • Influenza A Virus, H7N9 Subtype / pathogenicity*
  • Influenza in Birds / epidemiology*
  • Influenza in Birds / transmission
  • Influenza in Birds / virology*
  • Influenza, Human / epidemiology
  • Influenza, Human / virology
  • Orthomyxoviridae Infections / virology
  • Poultry
  • Public Health
  • Virulence / genetics
  • Virus Replication