The comparative assessment was carried out concerning anti-oxidation activity of blood serum of patients with liver pathology using two chemiluminescent techniques with different models of free radical oxidation: «Hb-Н2О2-luminol» и «ABAP-luminol». The reliable but low correlation of results was established (r=0,798) related mainly to difference in mechanisms of initiation of free radicals and effect of blood serum on initiation process. This effect is stronger manifested in model «Hb-Н2О2-luminol». The discrepancy of results of measurement is more expressed in patients with anomalous higher content of bilirubin in blood. Thereupon, oxidation model «ABAP-luminol» is to be considered as a more preferable for clinical practice.
Keywords: anti-oxidant activity; blood serum; chemiluminescence; free radical oxidation; luminol.