Silver Ions Detection via Nucleolipids Self-Assembly

Anal Chem. 2019 Feb 5;91(3):1692-1695. doi: 10.1021/acs.analchem.8b04066. Epub 2019 Jan 10.

Abstract

A novel hybrid bioinspired amphiphile featuring a cytosine moiety, which self-assembles into liposomes can be used to detect silver ions in aqueous media. The coordination of Ag+ ions by the nucleotide moiety increases membrane rigidity, which enhances the fluorescence of a common reporter, Thioflavin T. Ag+ can be sensed even at trace concentrations (3 ppb) with great specificity over other metals ions. These nucleotide based supramolecular structures can be used to detect silver ions in drinking water, demonstrating the robustness of this approach.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Benzothiazoles / chemistry
  • Deoxycytidine Monophosphate / analogs & derivatives*
  • Drinking Water / analysis
  • Fluorescent Dyes / chemistry
  • Glycerophospholipids / chemistry*
  • Liposomes / chemistry*
  • Silver / analysis*
  • Spectrometry, Fluorescence
  • Surface-Active Agents / chemistry
  • Water Pollutants, Chemical / analysis

Substances

  • Benzothiazoles
  • Drinking Water
  • Fluorescent Dyes
  • Glycerophospholipids
  • Liposomes
  • Surface-Active Agents
  • Water Pollutants, Chemical
  • Deoxycytidine Monophosphate
  • thioflavin T
  • Silver