Bone marrow-derived stem cells contribute to regeneration of the endometrium

Clin Exp Reprod Med. 2018 Dec;45(4):149-153. doi: 10.5653/cerm.2018.45.4.149. Epub 2018 Nov 30.

Abstract

Stem cells are undifferentiated cells capable of self-renewal and differentiation into various cell lineages. Stem cells are responsible for the development of organs and regeneration of damaged tissues. The highly regenerative nature of the human endometrium during reproductive age suggests that stem cells play a critical role in endometrial physiology. Bone marrow-derived cells migrate to the uterus and participate in the healing and restoration of functionally or structurally damaged endometrium. This review summarizes recent research into the potential therapeutic effects of bone marrow-derived stem cells in conditions involving endometrial impairment.

Keywords: Bone marrow; Endometrium; Stem cells.

Publication types

  • Review