[First report in Chile of a clinical isolate of Escherichia coli resistant to colistin harbouring the mcr-1 gene]

Rev Chilena Infectol. 2018 Aug;35(4):453-454. doi: 10.4067/s0716-10182018000400453.
[Article in Spanish]

Abstract

Recently it was described the plasmidial gene mcr-1 associated with colistin resistance. We screened by PCR and sequencing for gene mcr-1 in thirteen clinical isolates resistant to colistin. We observed amplification in one E. coli. To our knowledge, this is the first report of the presence of mcr-1 gene in Chile.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Colistin / pharmacology*
  • Drug Resistance, Bacterial / genetics*
  • Escherichia coli / drug effects
  • Escherichia coli / genetics*
  • Escherichia coli / isolation & purification*
  • Escherichia coli Infections / microbiology
  • Escherichia coli Proteins / isolation & purification*
  • Microbial Sensitivity Tests

Substances

  • Anti-Bacterial Agents
  • Escherichia coli Proteins
  • MCR-1 protein, E coli
  • Colistin