Draft Genome Sequence of Streptomyces cavourensis YBQ59, an Endophytic Producer of Antibiotics Bafilomycin D, Nonactic Acid, Prelactone B, and 5,11-Epoxy-10-Cadinanol

Huy Quang Nguyen; Nguyen Thi-Hanh Vu; Ha Hoang Chu; Son Ky Chu; Ha Hoang; Thanh Trung Tran; Cuong Nguyen; Linh Thi-My Dinh; Hien Thi-Thu Trinh; Tien Quyet Phi

doi:10.1128/MRA.01056-18

Draft Genome Sequence of Streptomyces cavourensis YBQ59, an Endophytic Producer of Antibiotics Bafilomycin D, Nonactic Acid, Prelactone B, and 5,11-Epoxy-10-Cadinanol

Microbiol Resour Announc. 2018 Sep 20;7(11):e01056-18. doi: 10.1128/MRA.01056-18. eCollection 2018 Sep.

Authors

Huy Quang Nguyen^#^{1

2

3}, Nguyen Thi-Hanh Vu^#², Ha Hoang Chu^{2

3}, Son Ky Chu⁴, Ha Hoang², Thanh Trung Tran², Cuong Nguyen⁵, Linh Thi-My Dinh², Hien Thi-Thu Trinh², Tien Quyet Phi^{2

3}

Affiliations

¹ University of Science and Technology of Hanoi (USTH), Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
² Institute of Biotechnology (IBT), Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
³ Graduate University of Science and Technology (GUST), Vietnam Academy of Science and Technology (VAST), Hanoi, Vietnam.
⁴ Hanoi University of Science and Technology (HUST), Hanoi, Vietnam.
⁵ Gene Technology Department, Vinmec Research Institute of Stem Cell and Gene Technology, Hanoi, Vietnam.

^# Contributed equally.

Abstract

This study reports the draft genome sequence of the endophytic Streptomyces cavourensis strain YBQ59, produces the antibiotics bafilomycin D, nonactic acid, prelactone B, and 5,11-epoxy-10-cadinanol. The draft genome sequence comprises ∼10.2 Mb, with a GC content of 64% and 8,958 predicted protein-coding genes, of which 14 gene clusters were found to associate with antibiotic biosynthetic pathways.