Automated Sleep Apnea Detection in Raw Respiratory Signals Using Long Short-Term Memory Neural Networks

IEEE J Biomed Health Inform. 2019 Nov;23(6):2354-2364. doi: 10.1109/JBHI.2018.2886064. Epub 2018 Dec 10.

Abstract

Sleep apnea is one of the most common sleep disorders and the consequences of undiagnosed sleep apnea can be very severe, ranging from increased blood pressure to heart failure. However, many people are often unaware of their condition. The gold standard for diagnosing sleep apnea is an overnight polysomnography in a dedicated sleep laboratory. Yet, these tests are expensive and beds are limited as trained staff needs to analyze the entire recording. An automated detection method would allow a faster diagnosis and more patients to be analyzed. Most algorithms for automated sleep apnea detection use a set of human-engineered features, potentially missing important sleep apnea markers. In this paper, we present an algorithm based on state-of-the-art deep learning models for automatically extracting features and detecting sleep apnea events in respiratory signals. The algorithm is evaluated on the Sleep-Heart-Health-Study-1 dataset and provides per-epoch sensitivity and specificity scores comparable to the state of the art. Furthermore, when these predictions are mapped to the apnea-hypopnea index, a considerable improvement in per-patient scoring is achieved over conventional methods. This paper presents a powerful aid for trained staff to quickly diagnose sleep apnea.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Databases, Factual
  • Female
  • Humans
  • Machine Learning
  • Male
  • Middle Aged
  • Monitoring, Physiologic / methods
  • Neural Networks, Computer*
  • Respiratory Physiological Phenomena*
  • Signal Processing, Computer-Assisted*
  • Sleep Apnea Syndromes / diagnosis*