[Comparative ultrasound study of gastric emptying between an isotonic solution and a nutritional supplement]

Braz J Anesthesiol. 2019 Mar-Apr;69(2):115-121. doi: 10.1016/j.bjan.2018.09.006. Epub 2018 Oct 24.
[Article in Portuguese]

Abstract

Background and objectives: Preoperative fasting may lead to undesirable effects in the surgical patient in whom there is a stimulus to ingesting clear liquids until 2 hours before anesthesia. The aim of this study was to evaluate the gastric emptying of two different solutions using ultrasound.

Methods: In a prospective, randomized, blind study, 34 healthy volunteers ingested 200 mL of two solutions without residues in two steps: an isotonic solution with carbohydrates, electrolytes, osmolarity of 292 mOsm.L−1, and 36 kcal; and other nutritional supplementation with carbohydrates, proteins, electrolytes, osmolarity of 680 mO.L−1, and 300 kcal. After 2 hours, a gastric ultrasound was performed to assess the antrum area and gastric volume, and the relation of gastric volume to weight (vol.w−1), whose value above 1.5 mL.kg−1 was considered a risk for bronchoaspiration. A p-value <0.05 was considered statistically significant.

Results: There was a significant difference between all parameters evaluated 2 hours after the ingestion of nutritional supplementation compared to fasting. The same occurred when the parameters between isotonic solution and nutritional supplementation were compared 2 hours after ingestion. Only one patient had vol.w−1 <1.5 mL.kg−1 2 hours after ingestion of nutritional supplementation; and only one had vol.w−1 >1.5 mL.kg−1 after ingestion of isotonic solution.

Conclusion: This study demonstrated that gastric emptying of equal volumes of different solutions depends on their constitution. Those with high caloric and high osmolarity, and with proteins present, 2 hours after ingestion, increased the gastric volumes, which is compatible with the risk of gastric aspiration.

Keywords: Bronchoaspiration; Broncoaspiração; Gastric ultrasound; Jejum pré‐operatório; Preoperative fasting; Ultrassonografia gástrica.

Publication types

  • Comparative Study
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Carbohydrates / administration & dosage
  • Dietary Supplements*
  • Electrolytes / administration & dosage
  • Energy Intake / physiology
  • Fasting / physiology
  • Female
  • Gastric Emptying / physiology*
  • Humans
  • Isotonic Solutions / administration & dosage*
  • Male
  • Osmolar Concentration
  • Prospective Studies
  • Proteins / administration & dosage
  • Stomach / diagnostic imaging
  • Ultrasonography / methods*
  • Young Adult

Substances

  • Carbohydrates
  • Electrolytes
  • Isotonic Solutions
  • Proteins