Beta-cell therapies for type 1 diabetes: Transplants and bionics

Cleve Clin J Med. 2018 Dec;85(12):931-937. doi: 10.3949/ccjm.85a.17088.

Abstract

Research continues toward the goal of treating type 1 diabetes by replacing insulin-producing beta cells. Ideally, such treatment would be safe and long-lasting and would eliminate the need for subcutaneous insulin replacement. This article reviews the current state of beta-cell replacement through transplant of the whole pancreas or of islet cells. It also looks at the "bionic" pancreas and other future challenges.

Publication types

  • Review

MeSH terms

  • Bionics / methods*
  • Diabetes Mellitus, Type 1 / surgery*
  • Humans
  • Insulin-Secreting Cells / transplantation*
  • Islets of Langerhans Transplantation / trends*
  • Pancreas Transplantation / trends*