To determine the impact of Cysticercus cellulose (C. cellulose) infection on mental health among school-aged children in Tibetan agricultural areas of Sichuan Province. Methods: In October 2015, all primary schools located in Tibetan agricultural areas in Yajiang, Ruoergai, and Muli county of Sichuan Province were selected as the research sites. All school-aged children at five- and six-grade were enrolled for the study by a multistage stratified cluster sampling method. Antibodies against C. cellulose were detected. Mental Health Test and questionnaire survey were conducted for school-aged children to collect data. The impact of C. cellulose infection on mental health among school-aged children was analyzed with the multilevel linear regression. Results: A total of 2 453 school-aged children were investigated. The C. cellulose seropositive rate was 6.03% (148/2 453). There were 0.16% (4/2 453) patients with seropositive accompanied by seizure, 2.28% (56/2 453) with seropositive accompanied by headache, 2.08% (51/2 453) with seropositive accompanied by frequent weak, and 0.41% (10/2 453) were seropositive accompanied by frequent nausea. The rate of C. cellulose infection was 4.53% (111/2 453). The mean score of the mental health test was 6.59±2.61. There were significant difference in score of mental health test in children whose demographic characteristics were different. The mental health scores of school-aged children were clustered at the school level. After controlling the factors of demographic characteristics, the result of multilevel model demonstrated that the factor of school-aged children with C. cellulose seropositive accompanied by headache was statistically significant (β=1.14, P=0.017). Conclusion: The status of C. cellulose infection among school-aged children in Tibetan agricultural areas is not optimistic. C. cellulose infection has impacted on mental health of local school-aged children. It is necessary to strengthen the prevention and control of C. cellulose infection in epidemic area.
目的：探索四川省藏族农业区学校儿童猪囊尾蚴(Cysticercus cellulose)感染对其心理健康的影响。方法：2015年10月，以四川省雅江县、若尔盖县、木里县所有位于藏族农业区的完全小学为研究现场，采用多阶段分层整群抽样方法，将学校中的五、六年级学校儿童整群纳入。对学校儿童进行猪囊尾蚴抗体检测、心理健康诊断测验以及问卷调查，运用多水平线性回归分析猪囊尾蚴感染对学校儿童心理健康的影响。结果：本次共调查2 453名学校儿童，猪囊尾蚴抗体阳性率为6.03%(148/2 453)，学校儿童猪囊尾蚴抗体阳性且伴有癫痫症状占0.16%(4/2 453)，抗体阳性且伴有头痛症状占2.28%(56/2 453)，抗体阳性且经常感到四肢无力占2.08%(51/2 453)，抗体阳性且经常感到恶心占0.41%(10/2 453)，感染率为4.53%(111/2 453)。学校儿童心理健康测验总均分为6.59±2.61，不同人口学特征的学校儿童心理健康测验得分差异均具有统计学意义(均P<0.01)。学校儿童心理健康分值在学校水平上存在聚集性，多水平模型结果表明：控制社会人口学特征后，学校儿童猪囊尾蚴抗体阳性且伴有头痛对其心理健康的独立影响具有统计学意义(β=1.14，P=0.017)。结论：藏族农业区学校儿童猪囊尾蚴感染现状不容乐观，猪囊尾蚴感染已对当地学校儿童的心理健康造成一定程度的影响，加强对疾病流行区的防控，保护儿童身心健康迫在眉睫。.