Understanding Fetal Heart Rate Patterns That May Predict Antenatal and Intrapartum Neural Injury

Semin Pediatr Neurol. 2018 Dec:28:3-16. doi: 10.1016/j.spen.2018.05.002. Epub 2018 Jun 20.

Abstract

Electronic fetal heart rate (FHR) monitoring is widely used to assess fetal well-being throughout pregnancy and labor. Both antenatal and intrapartum FHR monitoring are associated with a high negative predictive value and a very poor positive predictive value. This in part reflects the physiological resilience of the healthy fetus and the remarkable effectiveness of fetal adaptations to even severe challenges. In this way, the majority of "abnormal" FHR patterns in fact reflect a fetus' appropriate adaptive responses to adverse in utero conditions. Understanding the physiology of these adaptations, how they are reflected in the FHR trace and in what conditions they can fail is therefore critical to appreciating both the potential uses and limitations of electronic FHR monitoring.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cardiotocography*
  • Female
  • Fetal Diseases / diagnosis*
  • Heart Rate, Fetal*
  • Humans
  • Infant, Newborn
  • Nervous System Diseases / diagnosis*
  • Pregnancy