Absence of cytomegalovirus in gingivitis and chronic periodontitis in HIV-1 patients in Northern Brazil

Rev Soc Bras Med Trop. 2018 Nov-Dec;51(6):809-812. doi: 10.1590/0037-8682-0080-2018.

Abstract

Introduction: The influence of cytomegalovirus (CMV) on the progression of chronic periodontitis in HIV patients is poorly investigated.

Methods: ELISA was used for anti-CMV antibody IgG titer measurements and real-time polymerase chain reaction for qualitative and quantitative CMV detection. Data on the CD4 + T lymphocyte count and plasma HIV viral load were obtained from patient records.

Results: CMV DNA was detected in samples of subgingival biofilm in only three individuals, two of them with chronic periodontitis (4%) and one with gingivitis (3.3%).

Conclusions: The prevalence of CMV is very low both in HIV-1 patients with gingivitis and chronic periodontitis.

MeSH terms

  • Adult
  • CD4 Lymphocyte Count
  • Chronic Periodontitis / virology*
  • Cytomegalovirus / isolation & purification*
  • Cytomegalovirus Infections / virology
  • DNA, Viral
  • Female
  • Gingivitis / virology*
  • HIV Infections / complications*
  • HIV-1
  • Humans
  • Male
  • Real-Time Polymerase Chain Reaction
  • Viral Load

Substances

  • DNA, Viral