Impact of Acute Alcohol Exposure on P-Glycoprotein Function at the Blood-Brain Barrier Assessed Using ¹¹ C-Metoclopramide PET Imaging

Clin Pharmacol Ther. 2019 Apr;105(4):812-813. doi: 10.1002/cpt.1266. Epub 2018 Dec 4.

Authors

Sylvain Auvity^{1

2

3}, Nicolas Tournier¹

Affiliations

¹ UMR 1023 IMIV, Service Hospitalier Frédéric Joliot, CEA, Inserm, Université Paris Sud, CNRS, Université Paris-Saclay, Orsay, France.
² Inserm UMR-S 1144, Faculté de Pharmacie de Paris, Université Paris Descartes, Paris, France.
³ Assistance Publique-Hôpitaux de Paris, Hôpital Universitaire Necker-Enfants Malades, Paris, France.

PMID: 30515754
DOI: 10.1002/cpt.1266

No abstract available

Publication types

Letter
Comment

MeSH terms

ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1*
Blood-Brain Barrier*
Cytochrome P-450 CYP1A2
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP2D6
Cytochrome P-450 CYP3A
Ethanol
Metoclopramide
Positron-Emission Tomography

Substances

ATP Binding Cassette Transporter, Subfamily B
ATP Binding Cassette Transporter, Subfamily B, Member 1
Ethanol
Cytochrome P-450 CYP2C9
Cytochrome P-450 CYP1A2
Cytochrome P-450 CYP2C19
Cytochrome P-450 CYP2D6
Cytochrome P-450 CYP3A
Metoclopramide