Palmar pustular psoriasis associated with teriflunomide treatment

Abstract

Background: Cutaneous adverse effects of Teriflunomide have been rarely reported.

Objective and methods: We report a relapsing remitting multiple sclerosis patient that developed palmar pustular psoriasis within one month of teriflunomide initiation.

Results: Our patient required discontinuation of teriflunomide due to frequent recurrence of pustules with continuous need of local steroid treatment and resolved completely after teriflunomide discontinuation.

Conclusion: Pustular psoriasis can be triggered by medications but has not been previously reported in association with teriflunomide treatment, to the best of our knowledge.

Keywords: Adverse effect; Disease-modifying therapy; Multiple sclerosis; Pustular psoriasis; Teriflunomide.