Neuromyotonia in a horse

J Vet Intern Med. 2019 Jan;33(1):287-291. doi: 10.1111/jvim.15353. Epub 2018 Dec 3.

Abstract

This article describes the clinical and electromyographic findings of neuromyotonia in a 19-month-old male crossbred Quarter Horse that presented with stiffness and muscle asymmetry in the hind limbs as well as sacrococcygeal, paravertebral, and gluteal myokymia. An electromyographic study showed spontaneous continuous muscle fiber activity with high-frequency discharges, fibrillations, positive sharp waves, fasciculation potentials, and complex repetitive discharges. Histological examination of the gluteal muscle showed a mixed neurogenic and myopathic pattern. The findings are consistent with neuromyotonia.

Keywords: electromyography; equine; myokymia; myopathy; stiffness.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Electromyography / veterinary
  • Horse Diseases / diagnosis*
  • Horse Diseases / pathology
  • Horse Diseases / physiopathology
  • Horses
  • Isaacs Syndrome / diagnosis
  • Isaacs Syndrome / pathology
  • Isaacs Syndrome / physiopathology
  • Isaacs Syndrome / veterinary*
  • Membrane Glycoproteins
  • Muscle, Skeletal / pathology
  • Muscle, Skeletal / physiopathology
  • Receptors, Interleukin-1

Substances

  • Membrane Glycoproteins
  • Receptors, Interleukin-1
  • TIRAP protein, human