Dehydrative Allylation between Aldehydes and Allylic Alcohols through Synergistic N-Heterocyclic Carbene/Palladium Catalysis

Abstract

Dehydrative allylation between widely available aldehydes and allylic alcohols to afford β,γ-unsaturated ketones was enabled by a synergistic merger of a thiazolium N-heterocyclic carbene catalyst and a palladium-bisphosphine catalyst.

Keywords: aldehyde; carbene; dehydrative allylation; palladium; synergistic catalysis.