Data on characterization of magnetic nanoparticles stabilized with fusion protein of Barstar and C-term part of Mms6

Victoria O Shipunova; Polina A Kotelnikova; Ulkar F Aghayeva; Oleg A Stremovskiy; Alexey A Schulga; Maxim P Nikitin; Sergey M Deyev

doi:10.1016/j.dib.2018.10.173

Data on characterization of magnetic nanoparticles stabilized with fusion protein of Barstar and C-term part of Mms6

Data Brief. 2018 Nov 3:21:1659-1663. doi: 10.1016/j.dib.2018.10.173. eCollection 2018 Dec.

Authors

Victoria O Shipunova^{1

2

3}, Polina A Kotelnikova¹, Ulkar F Aghayeva¹, Oleg A Stremovskiy¹, Alexey A Schulga¹, Maxim P Nikitin³, Sergey M Deyev^{1

2}

Affiliations

¹ Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, 16/10 Miklukho-Maklaya Street, Moscow 117997, Russia.
² National Research Nuclear University MEPhI, Kashirskoe shosse 31, Moscow 115409, Russia.
³ Moscow Institute of Physics and Technology (State University), 9 Institutskiy per., Dolgoprudny, Moscow Region 141700, Russia.

Abstract

Mms6 is a protein that plays crucial role in the biomineralization and formation of magnetosomes in magnetotactic bacteria Magnetospirillum magneticum (strain AMB-1). We developed a fusion protein of C-term part of Mms6 and Barstar (natural inhibitor of ribonuclease Barnase), namely, Bs-C-Mms6. This protein successfully stabilized uncoated monocrystalline Fe₃O₄ magnetite nanoparticles in buffered solutions. Here, we present data regarding the synthesis and characterization of magnetite nanoparticles stabilized with Bs-C-Mms6. For further interpretation of the data presented in this article, please see the research article 'Self-assembling nanoparticles biofunctionalized with magnetite-binding protein for the targeted delivery to HER2/neu overexpressing cancer cells' (Shipunova et al., 2018) [1].