Data on a rat infection model to assess porous titanium implant coatings

M Croes; H de Visser; B P Meij; K Lietart; B C H van der Wal; H C Vogely; A C Fluit; C H E Boel; J Alblas; H Weinans; S Amin Yavari

doi:10.1016/j.dib.2018.10.157

Data on a rat infection model to assess porous titanium implant coatings

Data Brief. 2018 Nov 2:21:1642-1648. doi: 10.1016/j.dib.2018.10.157. eCollection 2018 Dec.

Authors

M Croes¹, H de Visser¹, B P Meij², K Lietart^{3

4}, B C H van der Wal¹, H C Vogely¹, A C Fluit⁵, C H E Boel⁵, J Alblas¹, H Weinans^{1

6

7}, S Amin Yavari¹

Affiliations

¹ Department of Orthopedics, University Medical Center Utrecht, Utrecht, the Netherlands.
² Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands.
³ 3D Systems - LayerWise NV, Leuven, Belgium.
⁴ Department of Metallurgy and Materials Engineering, KU Leuven, Leuven, Belgium.
⁵ Department of Medical Microbiology, University Medical Center Utrecht, Utrecht, the Netherlands.
⁶ Department of Biomechanical Engineering, Delft University of Technology, Delft, the Netherlands.
⁷ Department of Rheumatology, University Medical Center Utrecht, Utrecht, the Netherlands.

Abstract

A model is needed to study the effectiveness of different anti-bacterial coatings on complex metal implants in a bone environment. This article shares data on the design of porous titanium implants for intramedullary implantation in the proximal rat tibia. The implant length, diameter and porosity were optimized after testing on cadaveric specimens. This article shares data on which parameters are critical to establish a chronic implant infection in Sprague Dawley rats when using the new implant design. To this end, different strains of Staphylococcus aureus and inoculation doses were investigated.