Recent advances in pharmaceutical dosage forms and devices using additive manufacturing technologies

Christos I Gioumouxouzis; Christina Karavasili; Dimitrios G Fatouros

doi:10.1016/j.drudis.2018.11.019

Recent advances in pharmaceutical dosage forms and devices using additive manufacturing technologies

Drug Discov Today. 2019 Feb;24(2):636-643. doi: 10.1016/j.drudis.2018.11.019. Epub 2018 Nov 29.

Authors

Christos I Gioumouxouzis¹, Christina Karavasili¹, Dimitrios G Fatouros²

Affiliations

¹ Department of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
² Department of Pharmacy, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece. Electronic address: dfatouro@pharm.auth.gr.

PMID: 30503803
DOI: 10.1016/j.drudis.2018.11.019

Abstract

The era of 'one-size-fits-all' treatment approaches is becoming history for pharmaceutical manufacturing with the future encountering a revolution in drug development through the introduction of additive manufacturing technologies. The innovative elements of this disruptive technology will affect all shareholders of the pharmaceutical chain from the industrial sector to the dispensing facilities and, ultimately, the patient end-user. In this review, we provide an overview of the most recent advances in dosage forms and devices using additive manufacturing technologies, along with the regulatory landscape framing the development and safety requirements for 3D-printed drug products before entering the pharmaceutical market.

Publication types

Review

MeSH terms

Dosage Forms
Drug Delivery Systems*
Humans
Patient Satisfaction
Pharmaceutical Preparations / administration & dosage
Technology, Pharmaceutical / methods*

Substances

Dosage Forms
Pharmaceutical Preparations