Novel complication of Flakka: Stevens-Johnson syndrome/Toxic epidermal necrolysis overlap

Am J Emerg Med. 2019 Mar;37(3):562.e1-562.e3. doi: 10.1016/j.ajem.2018.11.037. Epub 2018 Nov 24.

Abstract

Flakka, as the newest member of the synthetic cathinone group, is a substance with serious cardiovascular, neurological, psychiatric, infectious effects and addictive potential. There are only a few case reports and laboratory studies in the literature and there is no dermatological side effects reported yet. We present the first Stevens-Johnson syndrome/Toxic epidermal necrolysis (SJS/TEN) overlap case after Flakka use.

Keywords: Bath salts; Flakka; Stevens-Johnson syndrome; Synthetic cathinone.

Publication types

  • Case Reports

MeSH terms

  • Anti-Inflammatory Agents / therapeutic use
  • Designer Drugs / adverse effects*
  • Emergency Service, Hospital
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use
  • Male
  • Methylprednisolone / therapeutic use
  • Pentanones / adverse effects*
  • Pyrrolidines / adverse effects*
  • Stevens-Johnson Syndrome / drug therapy
  • Stevens-Johnson Syndrome / etiology*
  • Stevens-Johnson Syndrome / pathology
  • Young Adult

Substances

  • Anti-Inflammatory Agents
  • Designer Drugs
  • Immunoglobulins, Intravenous
  • Pentanones
  • Pyrrolidines
  • 1-phenyl-2-(1-pyrrolidinyl)-1-pentanone
  • Methylprednisolone