Genetic diversity and haplotype structure of 27 Y-STR loci in a Yanbian Korean population from Jilin Province, Northeast China

Yequan Wang; Shuyue Li; Zhen Dang; Xia Kong; Yongji Zhang; Li Ma; Dan Wang; Han Zhang; Changzheng Li; Wen Cui

doi:10.1016/j.legalmed.2018.11.010

Genetic diversity and haplotype structure of 27 Y-STR loci in a Yanbian Korean population from Jilin Province, Northeast China

Leg Med (Tokyo). 2019 Feb:36:110-112. doi: 10.1016/j.legalmed.2018.11.010. Epub 2018 Nov 22.

Authors

Yequan Wang¹, Shuyue Li², Zhen Dang³, Xia Kong⁴, Yongji Zhang⁵, Li Ma⁴, Dan Wang⁶, Han Zhang³, Changzheng Li³, Wen Cui⁷

Affiliations

¹ Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Forensic Science Center of Jining Medical University, Jining, Shandong 272067, PR China. Electronic address: wangyequan1103@163.com.
² Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Forensic Science Center of Jining Medical University, Jining, Shandong 272067, PR China; Department of Forensic Medicine, Yanbian University Medical College, Yanji, Jilin, PR China.
³ Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Forensic Science Center of Jining Medical University, Jining, Shandong 272067, PR China.
⁴ The First People's Hospital Affiliated to Jining Medical University, 272067, PR China.
⁵ Department of Forensic Medicine, Yanbian University Medical College, Yanji, Jilin, PR China. Electronic address: zhangyj@ybu.edu.cn.
⁶ Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Jining, Shandong, PR China; College of Pharmaceutical Science, Zhejiang University, Hangzhou, Zhejiang, PR China.
⁷ Institute of Forensic Medicine and Laboratory Medicine, Jining Medical University, Forensic Science Center of Jining Medical University, Jining, Shandong 272067, PR China. Electronic address: cuiwenmdd@163.com.

PMID: 30502537
DOI: 10.1016/j.legalmed.2018.11.010

Abstract

In this study, 27 Y-STRs were analyzed in 347 male individuals from the Yanbian Korean population. Haplotype diversity (HD) and discrimination capacity (DC) values were calculated. Pairwise R_st values were evaluated in AMOVA analysis and visualized through multidimensional scaling (MDS). Yflier Plus system indicated higher Discrimination Power (DP), HD and DC which is 0.9969, 0.9998 and 0.9769. There is no significant genetic distance between Yanbian Koreans and South Koreans, however, there is a great distance from Chinese Han population. The present results may provide useful information for paternal lineages in forensic cases and increase our understanding of the genetic relationships between Yanbian Korean and other groups.

Keywords: Genetic diversity; Haplotype; Y-STR; Yanbian Korean.

MeSH terms

Asian People / ethnology
Asian People / genetics
China
Chromosomes, Human, Y / genetics*
Genetic Loci / genetics*
Genetic Variation / genetics*
Genetics, Population*
Haplotypes / genetics*
Humans
Male
Microsatellite Repeats / genetics*