Prediction of Hepatocellular Carcinoma After Sustained Virological Responses Using Magnetic Resonance Elastography

Mayu Higuchi; Nobuharu Tamaki; Masayuki Kurosaki; Keiya Watakabe; Leona Osawa; Wan Wang; Mao Okada; Takao Shimizu; Kenta Takaura; Hitomi Takada; Shun Kaneko; Yutaka Yasui; Kaoru Tsuchiya; Hiroyuki Nakanishi; Jun Itakura; Yuka Takahashi; Namiki Izumi

doi:10.1016/j.cgh.2018.11.046

Prediction of Hepatocellular Carcinoma After Sustained Virological Responses Using Magnetic Resonance Elastography

Clin Gastroenterol Hepatol. 2019 Nov;17(12):2616-2618. doi: 10.1016/j.cgh.2018.11.046. Epub 2018 Nov 28.

Authors

Mayu Higuchi¹, Nobuharu Tamaki¹, Masayuki Kurosaki¹, Keiya Watakabe¹, Leona Osawa¹, Wan Wang¹, Mao Okada¹, Takao Shimizu¹, Kenta Takaura¹, Hitomi Takada¹, Shun Kaneko¹, Yutaka Yasui¹, Kaoru Tsuchiya¹, Hiroyuki Nakanishi¹, Jun Itakura¹, Yuka Takahashi¹, Namiki Izumi²

Affiliations

¹ Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan.
² Department of Gastroenterology and Hepatology, Musashino Red Cross Hospital, Tokyo, Japan. Electronic address: izumi012@musashino.jrc.or.jp.

PMID: 30502507
DOI: 10.1016/j.cgh.2018.11.046

Abstract

Direct acting antivirals (DAAs) have made it possible for most patients to achieve sustained virologic responses (SVR).¹ However, some patients developed hepatocellular carcinoma (HCC) even after the eradication of hepatitis C virus²; therefore, it is clinically important to identify patients with a high risk of HCC development after SVR.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Age Factors
Aged
Antiviral Agents / therapeutic use
Carcinoma, Hepatocellular / epidemiology*
Elasticity Imaging Techniques*
Female
Hepatitis C, Chronic / drug therapy*
Humans
Liver Cirrhosis / diagnostic imaging*
Liver Neoplasms / epidemiology*
Male
Sustained Virologic Response
alpha-Fetoproteins / analysis

Substances

Antiviral Agents
alpha-Fetoproteins