Regulation of iNOS on Immune Cells and Its Role in Diseases

Int J Mol Sci. 2018 Nov 29;19(12):3805. doi: 10.3390/ijms19123805.

Abstract

In recent years, there have been many studies on the function of nitric oxide synthase (NOS) in experimental animals and humans. This review analyzes and explores the relationship between inducible nitric oxide synthase (iNOS) and T cells, macrophages, and dendritic cell et al. differentiation using data based on laboratory research, highlighting recent NOS laboratory research. Our insights into research prospects and directions are also presented.

Keywords: T cells; dendritic cells; iNOS; macrophages.

Publication types

  • Review

MeSH terms

  • Animals
  • Dendritic Cells / enzymology
  • Humans
  • Macrophages / enzymology
  • Nitric Oxide Synthase Type II / genetics
  • Nitric Oxide Synthase Type II / metabolism*
  • T-Lymphocytes / enzymology

Substances

  • Nitric Oxide Synthase Type II