In Situ Generation of Zinc Oxide Nanobushes on Microneedles as Antibacterial Coating

SLAS Technol. 2019 Apr;24(2):181-187. doi: 10.1177/2472630318812350. Epub 2018 Nov 30.

Abstract

This paper introduces a facile and scalable method to generate a layer of antibacterial coating on microneedles. The antibacterial coating (i.e., zinc oxide nanobushes) is generated on the surface of gold-coated polystyrene microneedles using the hydrothermal growth method. The antimicrobial property is examined using the agar diffusion test with both gram-positive and gram-negative bacteria.

Keywords: antibacterial coating; microneedles; skin; zinc oxide nanobushes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anti-Bacterial Agents / chemical synthesis*
  • Anti-Bacterial Agents / pharmacology*
  • Gold
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Nanostructures*
  • Polystyrenes
  • Surface Properties*
  • Zinc Oxide / chemical synthesis*
  • Zinc Oxide / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Polystyrenes
  • Gold
  • Zinc Oxide