Treatment-related Focal Nodular Hyperplasia Mimicking Liver Metastases

J Pediatr Hematol Oncol. 2019 Mar;41(2):138-139. doi: 10.1097/MPH.0000000000001362.

Abstract

A 7-year-old patient with a stage 4 neuroblastoma underwent chemotherapy, surgery, myeloablative therapy, external beam radiotherapy, and Isoretinoin treatment. A posttreatment magnetic resonance examination performed administering gadoteric acid as contrast agent showed 2 new hypervascular hepatic lesions, suspicious for metastases. A second magnetic resonance imaging performed using a liver-specific contrast medium (gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid) demonstrated that these lesions were consistent with treatment-related focal nodular hyperplasia.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Child
  • Contrast Media / administration & dosage*
  • Female
  • Gadolinium DTPA / administration & dosage*
  • Humans
  • Liver Neoplasms* / diagnostic imaging
  • Liver Neoplasms* / secondary
  • Liver Neoplasms* / therapy
  • Magnetic Resonance Imaging*
  • Neoplasm Metastasis
  • Neuroblastoma* / diagnostic imaging
  • Neuroblastoma* / therapy

Substances

  • Contrast Media
  • gadolinium ethoxybenzyl DTPA
  • Gadolinium DTPA