Ligand-based drug design of novel aldose reductase inhibitors

Future Med Chem. 2018 Nov;10(21):2493-2496. doi: 10.4155/fmc-2018-0127. Epub 2018 Nov 30.
No abstract available

Keywords: aldose reductase inhibitors; diabetes mellitus Type 2; electrostatics; ligand-based drug design.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aldehyde Reductase / antagonists & inhibitors*
  • Diabetes Mellitus, Type 2 / drug therapy
  • Diabetes Mellitus, Type 2 / enzymology
  • Drug Design*
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / pharmacology*
  • Humans
  • Hydantoins / chemistry
  • Hydantoins / pharmacology

Substances

  • Enzyme Inhibitors
  • Hydantoins
  • Aldehyde Reductase