Variability in quantitative diffusion-weighted MR imaging (DWI) across different scanners and imaging sites: is there a potential consensus that can help reducing the limits of expected bias?

Eur Radiol. 2019 May;29(5):2243-2245. doi: 10.1007/s00330-018-5866-4. Epub 2018 Nov 28.

Abstract

• Variability of ADC measurements may be substantial across different MRI scanners and imaging sites. • DWI protocol standardization and increased awareness of frequent sources of error can help reducing the limits of expected bias. • Focusing on ADC change and normalized ADC values rather than on absolute measurements can facilitate consistent use of ADC in multi-center studies.

Keywords: Diffusion; Magnetic resonance imaging; Multi-center studies; Reproducibility of results.

Publication types

  • Editorial

MeSH terms

  • Bias
  • Consensus*
  • Diffusion Magnetic Resonance Imaging / methods*
  • Humans
  • Neoplasms / diagnosis*
  • Phantoms, Imaging*
  • Reproducibility of Results