Clinical management of drug-resistant bacteria in Australian hospitals: An online survey of doctors' opinions

Infect Dis Health. 2018 Mar;23(1):41-48. doi: 10.1016/j.idh.2017.11.003. Epub 2018 Jan 10.

Abstract

Background: To gain a better understanding of clinical practice for the treatment of common drug-resistant infections.

Methods: A web-based anonymous survey was developed to gain a better understanding of clinical practice of patients infected with drug-resistant bloodstream infections (BSI). The survey instrument was a questionnaire requesting doctors to provide their opinion on the most likely choice of an antibiotic, dose and route of administration for patients infected with a drug-resistant Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa or Enterococcus faecium.

Results: All of the survey participants (n = 28) were hospital-based doctors. Choice of therapy for drug-resistant E. coli and K. pneumoniae was uniform across survey participants. However, optimal treatment of ceftazidime-resistant P. aeruginosa and VRE was less clear.

Conclusion: The survey adds to the limited body of evidence in this clinical area and can be a useful tool for health economists in determining the additional cost of treating patients with drug-resistant infections.

Keywords: Australia; Drug-resistance; Health care surveys; Sepsis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / therapeutic use*
  • Australia
  • Bacteremia / drug therapy*
  • Bacteremia / microbiology
  • Drug Resistance, Bacterial*
  • Hospitals
  • Humans
  • Internet
  • Physicians*
  • Practice Patterns, Physicians'*
  • Surveys and Questionnaires

Substances

  • Anti-Bacterial Agents