Advances in cancer modeling: fluidic systems for increasing representativeness of large 3D multicellular spheroids

Biotechniques. 2018 Dec;65(6):312-314. doi: 10.2144/btn-2018-0153.

Filippo Piccinini¹, Ilaria De Santis^{2

3}, Alessandro Bevilacqua^{2

4}

¹ Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST) IRCCS, Meldola (FC), Italy.
² Advanced Research Centre on Electronic Systems for Information & Communication Technologies 'E. De Castro' (ARCES), University of Bologna, Italy.
³ Interdepartmental Centre 'L. Galvani' for integrated studies of bioinformatics, biophysics & biocomplexity (CIG), University of Bologna, Italy.
⁴ Department of Computer Science & Engineering (DISI), University of Bologna, Italy.

No abstract available

Keywords: 3D cell cultures; microfluidic systems; multicellular spheroid; preclinical studies; tumor microenvironment.

MeSH terms