Efficacy and Safety of Intra-gastric Balloon Placement in Dialyzed Patients Awaiting Kidney Transplantation

Obes Surg. 2019 Feb;29(2):713-720. doi: 10.1007/s11695-018-3574-4.

Abstract

Background: The number of obese patients who are candidates for renal transplantation has considerably increased, but obesity can be a barrier to kidney transplantation. Weight loss is often difficult through diet alone. We studied the efficacy and tolerance of the intra-gastric balloon (IGB) procedure in obese patients who were undergoing dialysis and were candidates for a renal transplantation.

Patients and methods: Obese patients (BMI > 30 kg/m2) who were candidates for renal transplantation were prospectively included in the study between 2010 and 2012. The balloon was inserted and removed during a gastric endoscopy under general anesthesia. The treatment lasted 6 months. The end point was a decrease in BMI after 6 months. Body impedance spectrometry (BIS) and nutritional statute were evaluated initially and then after IGB removal.

Results: Seventeen patients (nine females and eight males) with a mean age of 53.4 years [19.4-69.4] were included. The decrease in body mass index (BMI) during the 6-month placement was 3 kg/m2 (from 37.7 to 34.4 kg/m2). The mean weight loss was 7 kg. The mean percentage of excess weight loss after 6 months was 20.2 (± 11.4). The tolerance was good without any complications. Eleven patients underwent kidney transplantation.

Conclusion: IGB in obese dialyzed patients who are candidates for renal transplantation is safe and effective. However, the amount of weight loss can vary.

Keywords: Awaiting kidney transplantation; Efficacy; Hemodialysis; Intra-gastric balloon; Obesity; Safety.

MeSH terms

  • Adult
  • Aged
  • Body Mass Index
  • Female
  • Gastric Balloon*
  • Humans
  • Kidney Transplantation
  • Male
  • Middle Aged
  • Obesity / therapy*
  • Prospective Studies
  • Renal Dialysis*
  • Waiting Lists*
  • Weight Loss
  • Young Adult