Advances in online methods for monitoring microbial growth

Biosens Bioelectron. 2019 Feb 1:126:433-447. doi: 10.1016/j.bios.2018.10.035. Epub 2018 Oct 18.

Abstract

Understanding the characteristics of microbial growth is of great significance to many fields including in scientific research, the food industry, health care, and agriculture. Many methods have been established to characterize the process of microbial growth. Online and automated methods, in which sample transfer is avoided, are popular because they can facilitate the development of simple, safe, and effective growth monitoring. This review focuses on advances in online monitoring methods over the last decade (2008-2018). We specifically focus on optic- and electrochemistry-based techniques, either through contact measurements or contactless measurement. Strengths and weaknesses of each set of methods are described and we also speculate on forthcoming trends in the field.

Keywords: Methodology; Microbial growth; Online monitoring; Real-time; Sensor.

Publication types

  • Review

MeSH terms

  • Bacteria / genetics
  • Bacteria / growth & development
  • Bacteria / isolation & purification*
  • Biosensing Techniques*
  • Electrochemistry*
  • Environmental Monitoring*
  • Humans