The Hard and Soft Wired Nature of the Olfactory Map

Trends Neurosci. 2018 Dec;41(12):872-874. doi: 10.1016/j.tins.2018.06.007.

Abstract

Across the animal kingdom, odors are known as potent stimuli that directly steer behavior. In 2007, Hitoshi Sakano and colleagues used the power of mouse genetics to manipulate the odor map in the olfactory bulb. Elegant behavioral, anatomical, and physiological analyses revealed an apparent dichotomy in how the brain interprets the odor map. Their work paved a way to think of behavioral contingencies as part of early olfactory processing, highlighting innate and learned pathways.

Keywords: innate; learned; odor maps; olfactory.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Brain Mapping*
  • Olfactory Bulb / anatomy & histology
  • Olfactory Bulb / physiology*
  • Olfactory Pathways / anatomy & histology
  • Olfactory Pathways / physiology*