Skin Cancer and Immunosuppression

Dermatol Clin. 2019 Jan;37(1):83-94. doi: 10.1016/j.det.2018.07.009. Epub 2018 Nov 1.

Abstract

Immunosuppressed patients are at significantly increased risk of developing cutaneous malignancies. These malignancies are often more aggressive compared with the general population and require multidisciplinary care. This article highlights the incidence and risk factors of cutaneous malignancies in this cohort. The treatment and prevention strategies are discussed. There continues to be a need for evidence-driven guidelines regarding the management of skin cancers in these patients.

Keywords: Chemoprevention; Human papillomavirus; Immunosuppression; Melanoma; Mohs micrographic surgery; Nonmelanoma skin cancer; Organ transplant recipients; Squamous cell carcinoma.

Publication types

  • Review

MeSH terms

  • Autoimmune Diseases / epidemiology
  • Carcinoma, Basal Cell / epidemiology
  • Carcinoma, Squamous Cell / epidemiology*
  • Carcinoma, Squamous Cell / pathology
  • Carcinoma, Squamous Cell / prevention & control*
  • Carcinoma, Squamous Cell / therapy
  • HIV Infections / epidemiology
  • Humans
  • Immunosuppression Therapy*
  • Leukemia, Lymphocytic, Chronic, B-Cell / epidemiology
  • Melanoma / epidemiology
  • Melanoma / therapy*
  • Neoplasm Staging
  • Organ Transplantation
  • Risk Factors
  • Sarcoma, Kaposi / epidemiology
  • Skin Neoplasms / epidemiology*
  • Skin Neoplasms / pathology
  • Skin Neoplasms / prevention & control*
  • Skin Neoplasms / therapy