Factors related to amblyopia in congenital ptosis after frontalis sling surgery

BMC Ophthalmol. 2018 Nov 21;18(1):302. doi: 10.1186/s12886-018-0962-4.

Abstract

Background: Amblyopia is a main concern in children undergoing frontalis sling surgery for repairing congenital ptosis. This study aimed to evaluate factors related to amblyopia in children undergoing frontalis sling surgery.

Methods: IRB-approved retrospective review of children under the age of 12 who received frontalis sling surgery. Preoperative demographic data, strabismus, margin reflex distance 1 (MRD1), lid fissure height, sling type, refraction errors, surgical outcome and amblyopia were evaluated.

Results: This study included 48 eyelid procedures performed in 38 patients. Median age was 4.0 years. Etiology was congenital ptosis in 42 eyes (87.5%) and blepharophimosis in 6 eyes (12.5%). Mersilene mesh was the sling material used in 36 eyes (75%), silicone in 6 eyes (12.5%), and polytetrafluoroethylene (PTFE) in 6 eyes (12.5%). Mean duration of follow-up was 27.8 ± 25.0 months (range, 3 to 128 months). Amblyopia was observed in 17 eyes (35.4%) at the final follow-up. Factors significantly associated with final amblyopia included blepharophimosis (p = 0.017), preoperative MRD1 ≤ - 1.0 mm (p = 0.038), preoperative lid fissure ≤4.5 mm (p = 0.035), preoperative anisometropia (spherical equivalent) (p = 0.011), and postoperative astigmatism (p = 0.026).

Conclusions: Study results suggest that blepharophimosis, preoperative MRD1 ≤ - 1.0 mm, preoperative lid fissure ≤4.5 mm, preoperative anisometropia (spherical equivalent), and postoperative astigmatism are associated with amblyopia after frontalis sling surgery in patients with congenital ptosis.

Keywords: Amblyopia; Congenital ptosis; Frontalis sling suspension; Mersilene mesh; Polytetrafluoroethylene; Silicone rode.

MeSH terms

  • Amblyopia / etiology*
  • Anisometropia / complications
  • Astigmatism / complications
  • Blepharoptosis / surgery*
  • Child
  • Child, Preschool
  • Eyelids / surgery*
  • Female
  • Humans
  • Male
  • Oculomotor Muscles / surgery*
  • Postoperative Complications / etiology*
  • Retrospective Studies